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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b51e0d7628dd71ab207aaa1c3dccc2653f82d26618b16e193a035dc155ad148' 
  AND token = 'FODIZDZ1wlC0QNRmvQ1JQTYO6rEhqGjxJ37YiJPVukw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}