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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '456ad039c0932d512fc383cce0b2a2d481fd8e6c0bf1970ed7db3eb2594febf9' 
  AND token = 'BQAPoMtKbicBfq5OIVT3Nj1WTJnwmfPYW/1szQ2rFWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}