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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '334ffaafdbd3648adf96d7bb5d5a20303afa7ad9534d4622abf7bb16f5a4ae31' 
  AND token = 'z0/p1Q51kbUoMeFl+0VvwjmadUDF4Njh43u1/yry7sI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}