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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fcf764db296071d1aff3fe3c4e3c16b0afc0481257e8d7b3859ca53bb63c386' 
  AND token = 'eRyvkq2d61/vePsxrzHNkZ+DUxScBgWB5BQ7TpaKCTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}