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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a249b835473d6547b387c2e7a73e7fc3ceed465227c7408be637033d00890e9a' 
  AND token = '7rwAjM//GVTEHhYtwNLvlNdUd4d20V5UNZ/T/z29GtU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}