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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '96f180aa1fceb580e992929bfd4ecdbbae030645ef74608b6e0914d932abbc49' 
  AND token = 'zZhqDL7rUgM/mSGjFqQ9U0rIePm5dlw8nxvwvh0fDSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}