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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f341c1d4475940bba69d8086a3004c804ff43795789d9997f424632279dc0154' 
  AND token = '4W89m4kLQ6lQuWf3LT5RnAG1hCYLFo+tmIM7ZTrF8i4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}