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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6feaca6db89f538ed53fbe162d179b31fa2a030a42b6e294df43d39b411abb0b' 
  AND token = 'XCqhyfoby1jTqilAJl+zUSHY3JtFJ2E0zAXimLh1Oqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}