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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79c183519f3a8c3fae23da7f2925e5ccc1f82f95f0380012d72da700991f7eaa' 
  AND token = 'TM95V0rLVcoN4IFKOXW3a4M6pvVo71QHkbyj/q1j+cA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}