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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40ec33e4acb7adbf150c44837cfeb68abdff6799c1b20dbc2fb386e4058a28b1' 
  AND token = 'PLb4gjlTc8ZEKyxAE9OSGzb4O0C7UxBF64j/T3hynTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}