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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '812f310aefaf9fdeca0f58c3b494f1c9573081d4704be58afdc4ece399cdf268' 
  AND token = 'ULVQVAmTQCCZBfWLEN4bFgnst8X5qeSZX7Sb75fgteE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}