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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd82b6311c5c2fa0294e88322ec2937b2bb6f5889765af181bc1c29ddd0905610' 
  AND token = 'r1/DX7mZ6xxIpLib8mcS2Zd7Tm2j6TqqM+ER2nwObIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}