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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db1e70d5ce95d2f41910c2d81e4b3aa12e6e27e27096eea79e68eb6d60189be4' 
  AND token = 'CV2NYHY/bvVgowGNvarAEdAjdBN1wjqzZbX8K8LnB+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}