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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9755b86264d002d5780921e8cbb86713e7f71cf0caf559caab4213c18e5e7622' 
  AND token = 'zrDk+R87CSmc++6LvISsT6xLWJVvdXxb3fYmw5bNSaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}