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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4205a7007083a6764aef2d6e1a5d5f12678675c34b3befcdfb2d4415e5f899bf' 
  AND token = 'crCW6P8/d0rs1pEr/UxEZn7z/7aVMnumt2K4vp/ak2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}