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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '975ca1e448ed5fd16eda27051e425823d81d654e10f2afb661f5edec37fdab66' 
  AND token = 'W6M9/j1dp+sFNU+/KAkoxinpOggmmwidnoZ0HPkz5CQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}