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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee7f0e02543069f9cd508f5b1378f23b2ff67a8336c10d9acf1f86530b784d1f' 
  AND token = 'QDg5+pN9/4S0y7umnv9+QiSwfzN4udoqg92BkQ0k57I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}