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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e561888a33a82029bf7f0d3e36204ae3422f7f596b742d917c5dc6e06f26c79' 
  AND token = 'j30l0PkQOOU1F0kudiD7FYBpLnpSshCeMVLphX9ySmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}