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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e97bedd2fcc6074a13c783dc4bd275ce489a64759e12a41348929bd14fc79840' 
  AND token = 'axxdMY1i1+6ZUc9xlZYT4dOW2gRWnFpqV/34Tw+lbUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}