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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '016c7fcf027370ea054e2a8a08b252f7d9784a8cb7288c52ef33a655ced021ec' 
  AND token = '+Idd8qdZQL9mHHr+NokZexL7mpzMGJEzWJ97CQt2y4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}