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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ee545b42d19cde74c63308e4106a5813eabae0574d04cb2132d27c0f4fbe80a' 
  AND token = 'M7k0X5YjAXKzpLqmd27Wtb0NeVWmx6mm8nCVA6Uw0B4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}