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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6d2833daa0285c9a57d0137528619fe732710aeed57461efcf2d31649ddfc84' 
  AND token = 'pupn2zYYqF8Le18Qo+cmRbXrjtI2ksnoLtNos7Yd5Y8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}