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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e44192d00f4a78a8845ce2deac3df45dc98741451f18fc4d342d19fba791820c' 
  AND token = 'MuB5Vz+3hKb+IWAissh8v+GA3peqoyn9aOWCr6XWWZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}