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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9859f0f6543f97c70819a6b4c86acbef93c69bb314b0b0c81ca5029693dc542a' 
  AND token = 'O8wbANiYXxG0rYy5Oyj6h9GvsZFIQ5n5Z8SZJIgVKd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}