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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76405cc3a597e09a8a9963398de87a043191582203e520e60513b7f4c213d2e3' 
  AND token = '+KrWKGMBghWk6VGQabAtZWVES+oItiBldU36k6MqIRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}