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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e1e67ed6e56b32bc6f3790c97124e94ed8ec5cb28779caec24dee1de593375b' 
  AND token = 'k7IAnUozgJwJ0+GP/jUZeMoWj6Q/F9GFlPhllfrdlPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}