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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65b812e821e4cd83c7c92da5a9a08cabb8b097cdde2d4772ceb5ba7d331d6cf5' 
  AND token = 'wfXWS4PJZxvdeV2CHpzce8E2SRbdQqbWw2V1GdVtcX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}