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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbe78c77a2d5d6b21930154aa47df86562b290eba4b336ad24b88e810a6740bf' 
  AND token = '6UnO9qVAOfBwR4Tjsi55TB9GUPJfzin+r21vBkA9w0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}