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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5ed8adb139373979529ccca501704b55362532483cc4228a534e5d45d812dd1' 
  AND token = 'JQm7L0fYA1uI1BjjdDoGymKIDinOd8KvBk0rx5LIcnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}