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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a361c25751d67d84935a47c7755f85c4c3207b57d10b29a3a0ae5442780f9b92' 
  AND token = 'r06TfMp6GdtfbUJmxZkg5TdLcP3gpgf4LMCwv8GDd0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}