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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a39f9816118f0bb9d4277e3e4a11676049e5885a7bee98b45d99eb0a56a879b' 
  AND token = 'FGcbH/rKWOyxQyicIjhR9wvxK+ds9xGw8sYfYBXGKQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}