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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7891451a9a93c1da1fa3bd816981f73c5e5ad964dfe6b1d7d8312d570128e783' 
  AND token = 'YrUgE9jhYQ7+HunAH0SmPaPElkv2Dkizernb8qaOkKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}