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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c71459f7902ae635d333e0644f1f562d626eecd9981d5b896787de31c89c3fa5' 
  AND token = 'itTnxby81ng+7NhDdyNDUE4WG6tziyBHAofiwYoD3bI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}