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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0804e181eeaf885d00dbdae38ac9c5499287f802098de6bc27ada6e8899852cb' 
  AND token = 'JOeZXb21LtpmxNXa70eklQ9rMcqRe83Ws5f2OwL5QZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}