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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e564536e6e327e0ad8390343e2059196e3a3ef72cb6b371c3029b59bdc02d60a' 
  AND token = 'H7Ifx/6zlucoCn2lDS63MCQWmd35o9HeeMdUOsqCDx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}