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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e024a0427f5629c8eb400935b41ab168f7bf2a48bffe09216d186ec9246748a4' 
  AND token = 'WC09MN99y85hCZtvHdHzReq899pmA4U7Sl9HYNjH25o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}