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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c270e33f80cb5ff32476bdc01453e3bc05b1e50d975c8c69622ebc6a6af66a7a' 
  AND token = 'cHHKHqGDXIfdLXTJ9TP468Nobho3xGwQEp8+JKTQ/NE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}