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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e89c584704d07d3e560f59e30eaff65c25fd556873b64ea322f3456db83aef4' 
  AND token = 'IkeYDWG3PIWH/LQEFySRx6Vx8EQhTL+uRGEsfmAt57w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}