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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a362fe0a0b66949a9811b4097f1b18f86729f692f0cbe65b66442b714d85511' 
  AND token = '/5VnM69LrBIV2EwZyP3v4QKhoI9DbXvv7ts0CGP9csE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}