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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b3d017812e4365208a6c49e1d058bee9f8ffb9a3a12a583d804ab0bee9e7006' 
  AND token = 'olVB6of0Z9Am0wS1503CUB0bup7KJqe0vvuL79IX3Iw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}