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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd01100bc22e346c64e8e535d9ac0e0da882e347d9628317c2e40a12169020d30' 
  AND token = 'Jnzsy9+lJ+4ZZHRXTLz5LwWyHnuNArsaCM0cdwzULnU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}