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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d1318c7f03693184128e2cd9aea66882ab55532cf7fe0adacc80d1ddca2a1f5' 
  AND token = 'bx/a9+nsNaWl4i99q+i0HBLKD1bWPkTdgvGHYNcEn5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}