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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d5c55f59cbd6a3d33df74b51b4af3ec3933f5e094eb4c0bd0be022e1890216c' 
  AND token = 'D2Em88DgFJDt6NDV1436TZIRjjjAZNMK5zsl4Qsjyk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}