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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '485f519b05548093e66e4534d5d29b52f1a08615ac3f2a5cb807ff69a6072b4c' 
  AND token = 'QWFTTMm0DFUdn1y4onCPtllUwHc2RMaWWUxTSA3WOXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}