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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de13d9f050ef3576ddf0f56dcc2000ff246f2e15cebaa8f307935d6d2950eb9a' 
  AND token = 'G2WK1pNd/XURvICf6sv2nfS5coz1QPb+TGkLbF2no5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}