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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2669da16ee323ee1a7160e26b1fd1066c73bba307e457b31e85b439d5a22931' 
  AND token = 'tq3JyAvIoK5rwcw6gToM7rBYyZEiW578ZiYYFMAq2zc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}