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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fffc154dd3b644394ab47641da459fb2d691a28867bbb61f8c104e332f7bee0c' 
  AND token = '6f+xQvXq+nNih428mlyeyUD4RWUTCl3inskk1Q2yw5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}