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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c887f29969e04c585c3410cd8e194f1487d2dd180a2cacd3869a1d85380c63bd' 
  AND token = 'bJgMaEnH/TQg4f1nQVwbY3zCjHWtZVSBxqg6NrgoHHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}