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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44c726e94bba493b646688207339eb744d0bac7d0f378c9fda239ce0193e7077' 
  AND token = '2bjO+3Ofg1NEJEX4JFrOaEwG9bXqNIIItoFydisL0Hs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}