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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a449d839107ea5e788d07e601fd8455d26304f95ef604f43d185de0e45d4dc29' 
  AND token = 'gytOXOgZMZJ0UoBFhX5i/utoAKhBeQNiFlLfdIcUtic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}